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Chang Duk Jun


Chang Duk Jun

Gwangju Institute of Science and Technology, Republic of South Korea

Biography

Chang Duk Jun discovered several crucial molecules involved in the immunological synapse (IS). Among them, TAGLN2 localizes at the distal area of supramolecular activation clusters (d-SMAC) in IS and stabilizes actin structure that prolongs the duration of IS. In macrophages, TAGLN2 plays an important role by enhancing the phagocytic function of macrophages. He is also interested in mutual communication between T cells and antigen-presenting cells in the process of immune synapses and kinapses. 

Abstract

Abstract : An essential role for TAGLN2 in phagocytosis of lipopolysaccharide-activated macrophages