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Dhêmerson Souza de Lima


Dhêmerson Souza de Lima

University of São Paulo, Brazil

Biography

Dhêmerson Souza de Lima has expertise in evaluation molecular biology with the emphasis on immunology, working mainly on the following topics: tuberculosis, immunogenetics of pulmonary tuberculosis, and HLA class II and inflammasome genetics and the response immune to Mycobacterium spp. Recently he was reported that HLA-DRB1*04 gene and subtypes associated with pulmonary tuberculosis in Amazon Brazilian, and may be potential immunogenetic markers involved in disease.  Besides, he found that NLRP3-inflammasome genetics seems to be protective against the development active pulmonary tuberculosis, however, P2X7 is associated with increased susceptibility. Currently is Ph.D. student in work with innate immune response and pathway to activation inflammasome.

Abstract

Abstract : Activation of NLRP3-inflammasome in human monocyte-derived macrophages infected with Mycobacterium spp.