Jessy Satyadas Deshane
Associate Professor
University of Alabama at Birmingham
USA
Biography
Dr. Jessy Deshane is currently an Associate Professor of Medicine at UAB. Since starting her own laboratory in January 2011, she focused her laboratory research program on immune regulation by myeloid-derived regulatory cells (MDRCs) in chronic inflammatory lung diseases. Dr. Jessy team have recently identified and characterized these free radical producing myeloid-lineage cells as master regulators of allergic airway inflammation. Her laboratory is particularly interested in delineating mechanisms underlying the differentiation and function of MDRCs in the establishment and resolution of inflammation. They are currently investigating the novel hypothesis that MDRCs can produce neo-antigens that trigger dysregulated immune responses in asthma. The impact of environmental exposures on MDRCs and generation of neo-antigens is also of great interest to her lab. She has recently extended her program to investigate novel strategies to target immunosuppression by myeloid-lineage cells and to reprogram the metabolism in the tumor microenvironment. Her team anticipates that their strategies will enhance persistent memory response for lung cancer.
Research Interest
Immune regulation, Asthma, Molecular Immunology, Tumor, Cancer